Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562655 | 1.00 | RIPK1 (0.38) | RIPK1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL15445818 | 1.00 | RIPK1 (0.38) | RIPK1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL9562663 | 1.00 | RIPK1 (0.38) | RIPK1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL24170292 | 0.97 | RIPK1 (0.39) | RIPK1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL9562632 | 0.96 | RIPK1 (0.37) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15445821 | 0.96 | RIPK1 (0.37) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL9562614 | 0.96 | RIPK1 (0.37) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL9562621 | 0.96 | RIPK1 (0.37) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL13967524 | 0.96 | RIPK1 (0.40) | RIPK1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL15445793 | 0.96 | RIPK1 (0.40) | RIPK1HTR2AHTR2CHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |