Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222633 | 1.00 | HPGD (0.35) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9229432 | 0.99 | GPR119 (0.35) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9562574 | 0.99 | GPR119 (0.35) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9224961 | 0.99 | GPR119 (0.35) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9225555 | 0.97 | CYP1A2 (0.37) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9562579 | 0.97 | CYP1A2 (0.37) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9222630 | 0.92 | HPGD (0.37) | HPGDMEN1KMT2AGPR119CYP1A2 | |
| SCHEMBL9229333 | 0.92 | SLC6A4 (0.34) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9562790 | 0.92 | SLC6A4 (0.34) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL9229430 | 0.91 | HPGD (0.37) | HPGDMEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541793-A1 | VINYL COMPOUNDS AND LIQUID-CRYSTAL MEDIUM. | MERCK PATENT GMBH (DE) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992021734-A1 | VINYL COMPOUNDS AND LIQUID-CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1992-12-10 | — | — | WO | disclosed |