SCHEMBL9563165

SCHEMBL9563165

Cc1nn(-c2ccc(C#N)c(F)c2)c(C)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.56
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC34A1 Q06495 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6495326 0.86 AR (0.52) AR
SCHEMBL4239678 0.83 AR (0.50) AR
SCHEMBL6503760 0.79 AR (0.40) ARMEN1POLBKMT2ASLC34A1
SCHEMBL4296720 0.76 AR (0.80) AR
SCHEMBL4240991 0.75 AR (0.51) ARMEN1KMT2A
SCHEMBL4241463 0.75 AR (0.80) AR
SCHEMBL4240988 0.75 AR (0.51) ARMEN1KMT2A
SCHEMBL4234751 0.72 AR (0.62) AR
SCHEMBL4230973 0.72 AR (0.62) AR
SCHEMBL4237293 0.72 AR (0.62) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558999-A2 N-arylpyrazole derivatives as herbicides BAYER AG (DE) 1993-09-08 EP disclosed