Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239678 | 0.86 | AR (0.50) | ARCYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL9563165 | 0.86 | AR (0.56) | AR | |
| SCHEMBL4296720 | 0.79 | AR (0.80) | AR | |
| SCHEMBL4240991 | 0.78 | AR (0.51) | ARCYP11B1CYP11B2 | |
| SCHEMBL4240988 | 0.78 | AR (0.51) | ARCYP11B1CYP11B2 | |
| SCHEMBL4241463 | 0.78 | AR (0.80) | AR | |
| SCHEMBL2530213 | 0.73 | EGLN2 (0.48) | CYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL25181380 | 0.73 | STIM1 (0.46) | ARCYP11B1CYP11B2TRPV4 | |
| SCHEMBL6497436 | 0.73 | CTSK (0.42) | ARCYP11B1CYP11B2TRPV4 | |
| SCHEMBL19120677 | 0.72 | AR (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| US-5554580-A | N-aryl-substituted nitrogen-containing heterocycles intermediates and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| EP-0370332-B1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5006148-A | N-aryl-substituted nitrogen-containing heterocycles, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0370332-A1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |