Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563186 | 0.94 | PARP14 (0.48) | PARP14BCHELMNACYP2D6DRD4 | |
| SCHEMBL9563200 | 0.91 | PARP14 (0.40) | PARP14BCHEALDH1A1LMNAHPGDS | |
| SCHEMBL9563175 | 0.88 | PARP14 (0.42) | PARP14BCHEHPGDSHTR7 | |
| SCHEMBL9563205 | 0.83 | PARP14 (0.58) | PARP14BCHELMNACYP2D6DRD4 | |
| SCHEMBL9563202 | 0.83 | CYP2D6 (0.55) | PARP14BCHEALDH1A1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9563342 | 0.82 | CYP2D6 (0.54) | PARP14BCHEALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9563416 | 0.82 | PARP14 (0.46) | PARP14BCHEALDH1A1LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL9563234 | 0.81 | PARP14 (0.45) | PARP14BCHEALDH1A1LMNACYP2D6 | |
| SCHEMBL9563213 | 0.81 | HTR7 (0.40) | PARP14BCHEALDH1A1HTR7 | |
| SCHEMBL9563310 | 0.81 | BCHE (0.57) | PARP14BCHEALDH1A1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |