Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563263 | 0.92 | BCHE (0.52) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9563254 | 0.91 | BCHE (0.51) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| SCHEMBL9563173 | 0.90 | BCHE (0.45) | BCHEPARP14HTR1AHTR7DRD2 | |
| SCHEMBL9563184 | 0.89 | BCHE (0.48) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| SCHEMBL9563179 | 0.89 | BCHE (0.56) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| SCHEMBL9563339 | 0.88 | BCHE (0.55) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| SCHEMBL9563225 | 0.87 | HTR1A (0.48) | BCHEPARP14CYP2D6HTR1AHTR7 | |
| SCHEMBL9563285 | 0.87 | BCHE (0.46) | BCHEPARP14HTR1ADRD2HTR2A | |
| SCHEMBL9563309 | 0.87 | BCHE (0.55) | BCHEPARP14CYP2D6HTR1ADRD2 | |
| SCHEMBL9563384 | 0.87 | PARP14 (0.49) | BCHEPARP14CYP2D6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |