SCHEMBL9563372

SCHEMBL9563372

CC(C)OC(F)(C(=O)O)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL9385937 0.98 THRB (0.30) THRB
SCHEMBL11133396 0.81
SCHEMBL7650282 0.81
SCHEMBL11281288 0.79
SCHEMBL30400919 0.78 THRB (0.32) THRB
SCHEMBL24361245 0.75 TSHR (0.32)
SCHEMBL569197 0.72 TSHR (0.35) THRB
SCHEMBL7263307 0.72 TSHR (0.33)
SCHEMBL22305023 0.71
SCHEMBL9563367 0.71 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331367-B1 Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU (JP) 1993-12-08 EP disclosed
US-5051527-A Liquid crystal compounds having fluoroalkyl radical SHOWA SHELL SEKIYU K.K. (JP) 1991-09-24 US disclosed
EP-0331367-A2 Liquid crystal compounds having fluoroalkyl radical Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-06 EP disclosed
EP-0081053-B1 OPTICALLY ACTIVE FLUOROALKOXY-CARBOXYLIC ACID OR ITS DERIVATIVE Daikin Kogyo Co., Ltd. (JP) 1986-03-12 EP disclosed
US-4542238-A PERFLUORO-2-ALKOXY CARBOXYLIC ACID DAIKIN KOGYO CO., LTD. (JP) 1985-09-17 US disclosed
EP-0082252-B1 PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND Daikin Kogyo Co., Ltd. (JP) 1985-08-21 EP disclosed
US-4484993-A ULTRASONIC ENERGY DAIKIN KOGYO CO., LTD. (JP) 1984-11-27 US disclosed
EP-0082252-A1 Process for producing fluorine-containing organic compound Daikin Kogyo Co., Ltd. (JP) 1983-06-29 EP disclosed
EP-0081053-A1 Optically active fluoroalkoxy-carboxylic acid or its derivative Daikin Kogyo Co., Ltd. (JP) 1983-06-15 EP disclosed