Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.61 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.56 |
| ▸ | PNP | P00491 | 11/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662537 | 0.82 | TK1 (0.70) | TK1HPRT1PNP | |
| SCHEMBL9563503 | 0.80 | HPRT1 (0.69) | TK1HPRT1PNP | |
| SCHEMBL9563506 | 0.80 | HPRT1 (0.69) | TK1HPRT1PNP | |
| SCHEMBL9563440 | 0.80 | HSP90AB1 (0.44) | — | |
| SCHEMBL6272731 | 0.80 | TK1 (0.74) | TK1HPRT1PNP | |
| SCHEMBL29286376 | 0.79 | TK1 (0.76) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL9664766 | 0.78 | TK1 (0.68) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL9664760 | 0.78 | TK1 (0.68) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL15743134 | 0.78 | TK1 (0.76) | TK1HPRT1PNPUSP2TSHR | |
| SCHEMBL3793003 | 0.78 | TK1 (0.76) | TK1HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531597-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |