Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570374 | 0.83 | CYSLTR1 (0.59) | PDE10ACYSLTR2CYSLTR1 | |
| SCHEMBL19579777 | 0.75 | HTT (0.57) | PDE10AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3515049 | 0.75 | SMN1; SMN2 (0.45) | MAPTCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL5756958 | 0.74 | GABRA1 (0.39) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL5757410 | 0.74 | ABCB1 (0.33) | ALDH1A1 | |
| SCHEMBL5755405 | 0.72 | KCNH2 (0.30) | — | |
| SCHEMBL15389972 | 0.72 | AURKA (0.37) | MAPT | |
| SCHEMBL16421411 | 0.72 | PDE10A (0.64) | PDE10AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL27613190 | 0.72 | PDE10A (0.64) | PDE10AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL5758916 | 0.71 | GABRA1 (0.40) | CYP1A2GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574774-A1 | Substituted benzothiazolyl- and quinoxalyl methoxy-phenyl acetic acid derivatives | BAYER AG (DE) | 1993-12-22 | — | — | EP | disclosed |