SCHEMBL9564308

SCHEMBL9564308

O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(N3C(=O)c4ccc(C(=O)O)cc4C3=O)c1)C2=O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.72
NPSR1 Q6W5P4 1/20 0.68
S100B P04271 1/20 0.67
KMT2A Q03164 5/20 0.66
MEN1 O00255 4/20 0.66
ALDH1A1 P00352 2/20 0.66
MAPT P10636 1/20 0.66
RECQL P46063 1/20 0.66
GFER P55789 1/20 0.65
TDP1 Q9NUW8 1/20 0.64
POLB P06746 4/20 0.63
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA9 Q16790 3/20 0.62
CA4 P22748 2/20 0.62
LPAR1 Q92633 1/20 0.62
LPAR5 Q9H1C0 1/20 0.62
LPAR3 Q9UBY5 1/20 0.62
PTGER4 P35408 1/20 0.61
RAB9A P51151 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4230581 0.95 S100B (0.74) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL1618163 0.92 KMT2A (0.76) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL7567814 0.91 ESR1 (0.72) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL9458520 0.91 TDP1 (0.77) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL5012357 0.91 HSD17B10 (0.66) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL5013757 0.90 HSD17B10 (0.64) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL9458368 0.90 HSD17B10 (0.76) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL5012367 0.90 NPSR1 (0.68) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL9458717 0.88 HSD17B10 (0.63) HSD17B10NPSR1S100BKMT2AMEN1
SCHEMBL9206676 0.88 HSD17B10 (0.63) HSD17B10NPSR1S100BKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114158-A1 IMIDE-CONTAINING POLYOLS, METHOD FOR MAKING IMIDE-CONTAINING POLYOLS AND METHOD FOR USING THE IMIDE POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-22 WO disclosed
EP-0554741-A1 Amidoimidobisphenoles, their preparation and thermostables polymers derived thereof DSM Chemie Linz GmbH (AT) 1993-08-11 EP disclosed
US-4812377-A CONTAINS 2,3-DIHYDRO-1,3-DIOXO-1H-ISOINDOLE CARBOXYLIC ACIDS EASTMAN KODAK COMPANY (US) 1989-03-14 US disclosed