Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022118 | 0.76 | HPGD (0.59) | KDM4EGAARAB9AMAPTNPSR1 | |
| SCHEMBL10874394 | 0.72 | MAPT (0.48) | KDM4EGAARAB9AMAPTHPGD | |
| SCHEMBL3305713 | 0.70 | GAA (0.44) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL3305720 | 0.70 | GAA (0.44) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL3311251 | 0.70 | GAA (0.46) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL3311255 | 0.70 | GAA (0.46) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL3311258 | 0.70 | GAA (0.46) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL18359173 | 0.68 | HPGD (0.57) | KDM4EGAARAB9AMAPTNPSR1 | |
| SCHEMBL6462215 | 0.68 | MEN1 (0.56) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL9564391 | 0.68 | ALDH1A1 (0.44) | GAARAB9AMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |