Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692097 | 1.00 | MAPT (0.52) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL2692103 | 1.00 | MAPT (0.52) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL2688974 | 0.85 | MAPT (0.56) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL4971785 | 0.85 | MAPT (0.56) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL2690403 | 0.84 | MAPT (0.47) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL2690406 | 0.84 | MAPT (0.47) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL9564366 | 0.83 | GAA (0.50) | MAPTHPGDHTTALDH1A1GAA | |
| SCHEMBL9564371 | 0.83 | GAA (0.50) | MAPTHPGDHTTALDH1A1GAA | |
| SCHEMBL1162892 | 0.79 | MEN1 (0.62) | MAPTHPGDHTTALDH1A1RAB9A | |
| SCHEMBL8586678 | 0.77 | MAPT (0.56) | MAPTHPGDHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |