Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564371 | 1.00 | GAA (0.50) | GAAMAPTHPGDLMNAHTT | |
| SCHEMBL2692103 | 0.83 | MAPT (0.52) | GAAMAPTHPGDHTTALDH1A1 | |
| SCHEMBL2692097 | 0.83 | MAPT (0.52) | GAAMAPTHPGDHTTALDH1A1 | |
| SCHEMBL9564388 | 0.83 | MAPT (0.52) | GAAMAPTHPGDHTTALDH1A1 | |
| SCHEMBL10874394 | 0.82 | MAPT (0.48) | GAAMAPTHPGDLMNAHTT | |
| SCHEMBL10869367 | 0.81 | NR4A1 (0.43) | MAPTALDH1A1KMT2AMEN1CYP1A1 | |
| SCHEMBL9848064 | 0.77 | KMT2A (0.66) | GAAMAPTHPGDLMNAHTT | |
| SCHEMBL9564422 | 0.77 | CES2 (0.40) | MAPTHPGDCA1KMT2AMEN1 | |
| SCHEMBL9564413 | 0.77 | CES2 (0.40) | MAPTHPGDCA1KMT2AMEN1 | |
| SCHEMBL9564421 | 0.75 | KDM4E (0.49) | MAPTLMNAHTTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |