Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56403 | 0.87 | TSHR (0.63) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL15732719 | 0.86 | TSHR (0.42) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28545578 | 0.84 | TSHR (0.61) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| Ammonia Solution, Strong SCHEMBL29207431 | 0.84 | TSHR (0.61) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL1112991 | 0.83 | CYP3A4 (0.39) | TSHRPKMSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18395977 | 0.81 | LMNA (0.40) | TSHRPKMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15732730 | 0.81 | TSHR (0.36) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3795992 | 0.81 | TSHR (0.44) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2320799 | 0.80 | TSHR (0.57) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11131759 | 0.80 | TSHR (0.74) | TSHRPKMSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557786-A1 | Method of separation of 1,4-butanediol from hydrogenation mixtures | BASF Aktiengesellschaft (DE) | 1993-09-01 | — | — | EP | disclosed |