Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 12/20 | 0.43 |
| ▸ | ATF1 | P18846 | 11/20 | 0.43 |
| ▸ | XPO1 | O14980 | 4/20 | 0.43 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565080 | 0.86 | NFKB1 (0.42) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9564875 | 0.83 | NFKB1 (0.57) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9564859 | 0.81 | XPO1 (0.46) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL4592101 | 0.75 | MAPT (0.57) | NFKB1ATF1XPO1JUNNFKB2 | |
| Water SCHEMBL4593114 | 0.74 | MAPT (0.56) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL4592592 | 0.72 | KDM4E (0.72) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL9564861 | 0.71 | NFKB1 (0.58) | NFKB1ATF1XPO1JUNNFKB2 | |
| Water SCHEMBL4592788 | 0.71 | KDM4E (0.71) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL29003853 | 0.69 | NFKB1 (0.33) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL8398359 | 0.68 | NFKB1 (0.43) | NFKB1ATF1XPO1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |