Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CCR3 | P51677 | 11/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548972 | 0.88 | TP53 (0.54) | CCR3LMNATP53MAPT | |
| SCHEMBL10550102 | 0.84 | GNRHR (0.51) | CCR3GNRHRTP53CYP2D6 | |
| SCHEMBL9564956 | 0.79 | CYP1A2 (0.54) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9564883 | 0.78 | CYP1A2 (0.45) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9537582 | 0.77 | TP53 (0.53) | LMNATP53MAPT | |
| SCHEMBL9564763 | 0.77 | CYP1A2 (0.54) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10548374 | 0.76 | KCNH2 (0.47) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL9564885 | 0.76 | CYP1A2 (0.51) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL9564888 | 0.76 | CYP1A2 (0.51) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9564851 | 0.75 | CYP1A2 (0.54) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |