Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535114 | 0.92 | SLC6A9 (0.53) | TP53SLC6A9MAPTLMNAENPP2 | |
| SCHEMBL9536213 | 0.89 | TP53 (0.61) | TP53SLC6A9MAPTLMNAENPP2 | |
| SCHEMBL10548972 | 0.89 | TP53 (0.54) | TP53SLC6A9MAPTLMNAENPP2 | |
| SCHEMBL10552594 | 0.88 | LMNA (0.54) | TP53SLC6A9MAPTLMNAENPP2 | |
| Oxalic Acid SCHEMBL10550818 | 0.87 | SLC6A9 (0.51) | TP53SLC6A9MAPTLMNAENPP2 | |
| Oxalic Acid SCHEMBL10550824 | 0.87 | SLC6A9 (0.51) | TP53SLC6A9MAPTLMNAENPP2 | |
| Oxalic Acid SCHEMBL10550830 | 0.87 | SLC6A9 (0.51) | TP53SLC6A9MAPTLMNAENPP2 | |
| SCHEMBL9536847 | 0.87 | KCNH2 (0.49) | TP53POLB | |
| SCHEMBL9538693 | 0.87 | SLC6A9 (0.52) | TP53SLC6A9MAPTLMNAENPP2 | |
| SCHEMBL9535415 | 0.86 | SLC6A9 (0.55) | TP53SLC6A9MAPTLMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |