Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399333 | 0.79 | MAPT (0.46) | GAACYP1A2LMNAKMT2APKM | |
| SCHEMBL31741533 | 0.77 | MAPT (0.51) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL31568215 | 0.74 | GAA (0.50) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL24970320 | 0.73 | HTT (0.51) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL21896802 | 0.73 | SCN4A (0.50) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL17276517 | 0.72 | GAA (0.48) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL20570751 | 0.72 | SCN4A (0.46) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL17276714 | 0.72 | F2 (0.53) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL29014065 | 0.71 | CYP19A1 (0.49) | GAABCL9CTNNB1CYP1A2CYP2D6 | |
| SCHEMBL20567635 | 0.71 | SCN4A (0.51) | GAABCL9CTNNB1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567841-A2 | Fluorescently marked compounds, their preparation and use | MERCK PATENT GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |