Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 11/20 | 0.79 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193788 | 0.91 | KAT2B (0.97) | KAT2BCA12CA1CA9ALDH1A1 | |
| SCHEMBL9565234 | 0.91 | KAT2B (0.97) | KAT2BCA12CA1CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11713957 | 0.88 | KAT2B (0.90) | KAT2BCA12CA1CA9ALDH1A1 | |
| SCHEMBL8579476 | 0.83 | KAT2B (0.80) | KAT2BCA12CA1CA9ALDH1A1 | |
| SCHEMBL8529337 | 0.82 | KAT2B (0.68) | KAT2BCA12CA1CA9HSD17B10 | |
| SCHEMBL9234887 | 0.82 | KAT2B (0.61) | KAT2BCA12CA1CA9 | |
| SCHEMBL11189889 | 0.82 | KAT2B (0.77) | KAT2BCA12CA1CA9ALDH1A1 | |
| SCHEMBL9308688 | 0.79 | KAT2B (0.57) | KAT2BCA12CA1CA9 | |
| SCHEMBL1533676 | 0.78 | — | — | |
| SCHEMBL8533834 | 0.77 | KAT2B (1.00) | KAT2BALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5222014-A | — | — | None | — | — | JP | disclosed |
| JP-H05222014-A | BIS-ISOTHIAZOLONE AS MICROBICIDE IN WIDE RANGE | ROHM & HAAS CO | 1993-08-31 | — | — | JP | disclosed |
| EP-0539091-A1 | Novel bis-isothiazolones and the use thereof as microbicides | ROHM AND HAAS COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |