Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26570742 | 0.87 | TAAR1 (0.50) | TTRMEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL16809181 | 0.83 | CSNK1E (0.51) | CSNK1DCSNK1EMAPK14NPC1RAB9A | |
| SCHEMBL6509046 | 0.83 | MAOA (0.54) | ALOX5APFEN1MEN1KMT2ACA1 | |
| SCHEMBL30549059 | 0.83 | MAOA (0.54) | ALOX5APFEN1MEN1KMT2ACA1 | |
| SCHEMBL2093620 | 0.83 | TTR (0.39) | TTRALOX5APFEN1TRPA1GRM5 | |
| SCHEMBL5390122 | 0.82 | TTR (0.58) | TTRESR1MEN1KMT2AESR2 | |
| SCHEMBL14152886 | 0.81 | TTR (0.47) | TTRALOX5APFEN1TRPA1ESR1 | |
| Hydrochloric Acid SCHEMBL30833257 | 0.80 | TTR (0.56) | TTRESR1MEN1KMT2AMAPK14 | |
| SCHEMBL16127491 | 0.79 | IKBKB (0.53) | — | |
| SCHEMBL9249473 | 0.78 | TTR (0.43) | TTRALOX5APFEN1TRPA1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534388-A1 | Tungsten-imido catalysts for ring-opening metathesis polymerization of cycloolefins | HERCULES INCORPORATED (US) | 1993-03-31 | — | — | EP | disclosed |