Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258167 | 0.92 | MCHR1 (0.40) | MAPTLMNAPDE5AMCHR1KMT2A | |
| SCHEMBL1424639 | 0.92 | MCHR1 (0.40) | MAPTLMNAPDE5AMCHR1KMT2A | |
| SCHEMBL4791409 | 0.92 | MCHR1 (0.40) | MAPTLMNAPDE5AMCHR1KMT2A | |
| SCHEMBL5602712 | 0.92 | MCHR1 (0.40) | MAPTLMNAPDE5AMCHR1KMT2A | |
| SCHEMBL4443386 | 0.86 | MAPT (0.33) | MAPTALDH1A1LMNAHTTATM | |
| SCHEMBL3922564 | 0.84 | KDM4E (0.35) | MAPTALDH1A1LMNAHTTATM | |
| SCHEMBL20367066 | 0.83 | MAPT (0.40) | MAPTALDH1A1LMNAHTTATM | |
| SCHEMBL1905764 | 0.82 | PLA2G4B (0.35) | MAPTALDH1A1LMNAHTTATM | |
| SCHEMBL1906579 | 0.82 | PLA2G4B (0.35) | MAPTALDH1A1LMNAHTTATM | |
| SCHEMBL1311279 | 0.82 | MAPT (0.42) | MAPTALDH1A1LMNAHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548015-A1 | Tetramethylpiperidine compounds for use as stabilisers for organic materials | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |