Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297650 | 0.77 | CNR2 (0.52) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL25112299 | 0.74 | RAB9A (0.71) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL24898159 | 0.74 | RAB9A (0.66) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL9565311 | 0.73 | PREP (0.39) | RAB9AHDAC6MEN1TP53MAPT | |
| SCHEMBL10245110 | 0.72 | RAB9A (0.67) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL27841342 | 0.72 | RAB9A (0.52) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL13209963 | 0.71 | PTPN1 (0.54) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL7631322 | 0.71 | CNR2 (0.52) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL30301713 | 0.71 | CNR2 (0.52) | RAB9ACNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL5020895 | 0.71 | RAB9A (0.66) | RAB9ACNR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543245-A1 | Renin inhibiting amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-05-26 | — | — | EP | disclosed |