Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.64 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591 | 1.00 | MME (0.64) | MMEMMEL1ACEFFAR1 | |
| SCHEMBL17580886 | 0.87 | MME (0.53) | MMEMMEL1ACE | |
| SCHEMBL28578516 | 0.80 | MME (0.65) | MMEMMEL1ACE | |
| SCHEMBL18555598 | 0.79 | FFAR1 (0.57) | MMEMMEL1ACEFFAR1 | |
| SCHEMBL9565421 | 0.78 | MME (1.00) | MMEMMEL1ACE | |
| SCHEMBL7438041 | 0.77 | MME (0.59) | MMEMMEL1ACE | |
| SCHEMBL29007017 | 0.77 | MME (0.65) | MMEMMEL1ACE | |
| SCHEMBL10710074 | 0.74 | CPA3 (0.67) | MMEACEFFAR1 | |
| SCHEMBL1912584 | 0.72 | MME (0.80) | MMEMMEL1ACE | |
| SCHEMBL2878301 | 0.72 | MME (0.80) | MMEMMEL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | claimed |
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |