Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.86 |
| ▸ | ACE | P12821 | 7/20 | 0.86 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565424 | 0.98 | MME (0.86) | MMEACEMMEL1 | |
| Lbq-657 SCHEMBL9565416 | 0.93 | MME (1.00) | MMEACEMMEL1 | |
| Lbq-657 SCHEMBL1908575 | 0.93 | MME (1.00) | MMEACEMMEL1 | |
| Lbq-657 SCHEMBL489122 | 0.93 | MME (1.00) | MMEACEMMEL1 | |
| Lbq-657 SCHEMBL7433849 | 0.93 | MME (1.00) | MMEACEMMEL1 | |
| Lbq-657 SCHEMBL391633 | 0.93 | MME (1.00) | MMEACEMMEL1 | |
| SCHEMBL21098596 | 0.88 | MME (0.67) | MMEACEMMEL1 | |
| SCHEMBL9565409 | 0.88 | MME (0.81) | MMEACEMMEL1 | |
| SCHEMBL14890785 | 0.87 | MME (1.00) | MMEACE | |
| SCHEMBL14890786 | 0.87 | MME (1.00) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | claimed |
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |