Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565499 | 1.00 | TSHR (0.39) | TSHRTACR1TAAR1LMNAPDE4D | |
| SCHEMBL9565550 | 1.00 | TSHR (0.39) | TSHRTACR1TAAR1LMNAPDE4D | |
| SCHEMBL9565492 | 1.00 | TSHR (0.39) | TSHRTACR1TAAR1LMNAPDE4D | |
| SCHEMBL9565495 | 1.00 | TSHR (0.39) | TSHRTACR1TAAR1LMNAPDE4D | |
| SCHEMBL9565489 | 0.74 | TSHR (0.45) | TSHRTACR1EPHX2 | |
| SCHEMBL9565491 | 0.74 | TSHR (0.45) | TSHRTACR1EPHX2 | |
| SCHEMBL599216 | 0.74 | TSHR (0.45) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL1857390 | 0.73 | TSHR (0.48) | TSHRTACR1PDE4DGBA1UGCG | |
| SCHEMBL1857389 | 0.73 | TSHR (0.48) | TSHRTACR1PDE4DGBA1UGCG | |
| SCHEMBL763893 | 0.73 | TSHR (0.48) | TSHRTACR1PDE4DGBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554025-A2 | Fluorinated cyclobutyl purines and pyrimidines | E.R. SQUIBB & SONS, INC. (US) | 1993-08-04 | — | — | EP | disclosed |