Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.67 |
| ▸ | MGLL | Q99685 | 3/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304902 | 1.00 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBCNR2 | |
| SCHEMBL967401 | 1.00 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBCNR2 | |
| SCHEMBL24950547 | 1.00 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBCNR2 | |
| SCHEMBL7335792 | 0.98 | SMPD1 (0.64) | SMPD1MGLLTHRATHRBCNR2 | |
| SCHEMBL9307263 | 0.94 | SMPD1 (0.76) | SMPD1MGLLTHRATHRBCNR2 | |
| SCHEMBL29171402 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBPLA2G4B | |
| SCHEMBL29171445 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBPLA2G4B | |
| SCHEMBL14930509 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBPLA2G4B | |
| SCHEMBL9307505 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBPLA2G4B | |
| SCHEMBL29171438 | 0.94 | SMPD1 (0.67) | SMPD1MGLLTHRATHRBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |