Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616832 | 0.80 | KDM4E (0.46) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL7898939 | 0.79 | KDM4E (0.45) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL3659891 | 0.76 | KDM4E (0.62) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL30440591 | 0.76 | KDM4E (0.62) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL8394962 | 0.73 | KDM4E (0.44) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL1526798 | 0.72 | KDM4E (0.56) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL31543749 | 0.71 | KDM4E (0.54) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL531050 | 0.71 | KDM4E (0.54) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL28463055 | 0.71 | KDM4E (0.54) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL23888753 | 0.69 | KDM4E (0.58) | TP53KDM4ELMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | claimed |
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |