SCHEMBL531050

SCHEMBL531050

[Fe].c1ccc(-c2nnnc(-c3ccccn3)c2-c2ccccn2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
LMNA P02545 3/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
NPC1 O15118 6/20 0.52
TP53 P04637 4/20 0.52
RAB9A P51151 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALOX15 P16050 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
HTT P42858 2/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526798 0.98 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28463055 0.96 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Acetic Acid SCHEMBL28642244 0.85 KDM4E (0.44) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30440591 0.84 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL3659891 0.84 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4667108 0.83 KDM4E (0.45) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31055535 0.82 KDM4E (0.41) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11910164 0.75 KDM4E (0.81) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL31695013 0.75 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL391569 0.75 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10018625-B2 Use of female mammal's urine for determination of fetal gender related characteristics UROBIOLOGICS LLC (US) 2018-07-10 US claimed
EP-2863220-B1 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics UROBIOLOGICS LLC (US) 2017-09-06 EP claimed
US-20150316540-A1 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS UROBIOLOGICS LLC 2015-11-05 US claimed
US-9057720-B2 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics UROBIOLOGICS LLC (US) 2015-06-16 US claimed
EP-2863220-A2 Reducing/oxidizing activity of maternal urine as indicator of fetal gender related characteristics Urobiologics LLC (US) 2015-04-22 EP claimed
US-20140302537-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics OURNEXTBABY LLC 2014-10-09 US claimed
EP-2619573-A1 USE OF FEMALE MAMMAL'S URINE FOR DETERMINATION OF FETAL GENDER RELATED CHARACTERISTICS Urobiologics LLC (US) 2013-07-31 EP claimed
WO-2012036691-A1 USE OF FEMALE MAMMAL'S URINE FOR DETERMINATION OF FETAL GENDER RELATED CHARACTERISTICS UROBIOLOGICS LLC (US) 2012-03-22 WO claimed
US-20110230453-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics UROBIOLOGICS LLC (US) 2011-09-22 US claimed
EP-2257803-A2 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS Urobiologics LLC (US) 2010-12-08 EP claimed
US-20090233321-A1 Reducing/Oxidizing Activity of Maternal Urine As Indicator of Fetal Gender Related Characteristics UROBIOLOGICS LLC (US) 2009-09-17 US claimed
WO-2009114579-A2 REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS UROBIOGICS LLC (US) 2009-09-17 WO claimed
US-6177260-B1 SIMPLE, EFFICIENT METHOD OF ANALYZING THIOL GROUP CONTAINING PROTEINS, GLUTATHIONE, CYSTEINE, FLAVONOIDS, AND VITAMIN E BY CONTACTING IN ACTIVE AND DEACTIVE STATE WITH OXIDANT RESULTING IN CHANGE OF ABSORBANCE SPECTRA AND COMPARING THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2001-01-23 US claimed
CN-117310050-B Screening method of honeysuckle antioxidation quality markers 中国中医科学院中医药健康产业研究所 2024-02-09 CN disclosed
CN-117310050-A Screening method of honeysuckle antioxidation quality markers 中国中医科学院中医药健康产业研究所 2023-12-29 CN disclosed
WO-2023068778-A1 COMPOSITION FOR PREVENTION AND TREATMENT OF FEMALE MENOPAUSAL DISEASES COMPRISING PHYTOGEN AS ACTIVE INGREDIENT 리누 바이오 헬스 엘티디. 2023-04-27 WO disclosed
US-20050244983-A1 Method for measuring antioxidant status THE WESTERN AUSTRALIAN CENTRE FOR PATHOLOGY AND MEDICAL RESEARCH (AU) 2005-11-03 US disclosed
WO-2004034058-A1 A METHOD FOR MEASURING ANTIOXIDANT STATUS THE WESTERN AUSTRALIAN CENTRE FOR PATHOLOGY AND MEDICAL RESEARCH (AU) 2004-04-22 WO disclosed
US-6326034-B1 FROM YEAST OR SALTBUSH; REGULATE GLUCOSE AND LIPID METABOLISM, INSULIN; TREATMENT OF DIABETES, CARDIOVASCULAR DISEASES AND HYPERLIPIDEMIA; NONTOXIC NATURAL COMPOUNDS LTD (IL) 2001-12-04 US disclosed
WO-2001045701-A1 NATURAL EXTRACTED AND SYNTHETIC ANTIOXIDANT COMPOSITIONS NATURAL COMPOUNDS LTD. (IL) 2001-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230453-A1 Use of Female Mammal's Urine for Determination of Fetal Gender Related Characteristics SHBG, PGF, CYP19A1 KDM4E 4180/4885LMNA 1670/4885CCR1 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.