Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628228 | 0.92 | KDM4E (0.67) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL20018954 | 0.87 | KDM4E (0.64) | KDM4ETDP1TP53PKML3MBTL1 | |
| SCHEMBL9565657 | 0.84 | KDM4E (0.56) | KDM4ETDP1TP53PKML3MBTL1 | |
| SCHEMBL9565651 | 0.84 | KDM4E (0.56) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL17932777 | 0.83 | MEN1 (0.58) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL12628238 | 0.80 | TP53 (0.58) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL27256804 | 0.78 | TP53 (0.67) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL23609564 | 0.78 | TP53 (0.52) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL9958034 | 0.78 | MEN1 (0.52) | KDM4ETDP1TP53PKMMEN1 | |
| SCHEMBL18325244 | 0.78 | TP53 (0.52) | KDM4ETDP1TP53PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |