Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20018954 | 0.87 | KDM4E (0.64) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9565653 | 0.84 | KDM4E (0.56) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9565657 | 0.84 | KDM4E (0.56) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9565645 | 0.81 | KDM4E (0.55) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9565652 | 0.81 | KDM4E (0.51) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9565619 | 0.81 | KDM4E (0.51) | KDM4ETDP1LMNAL3MBTL1TGFBR1 | |
| SCHEMBL22043746 | 0.78 | TP53 (0.67) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL5589973 | 0.77 | KDM4E (0.78) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL4667110 | 0.77 | KDM4E (0.78) | KDM4ETDP1LMNAL3MBTL1ALOX15 | |
| SCHEMBL17932569 | 0.75 | KDM4E (0.67) | KDM4ETDP1LMNAL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |