Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611468 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL3611465 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL3609083 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL3609081 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ADRA2B | |
| SCHEMBL8136234 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8120918 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8154760 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10862554 | 0.68 | MEN1 (0.38) | KDM4EALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL13502976 | 0.68 | MEN1 (0.39) | KDM4EALDH1A1HPGDMAPK1POLB | |
| SCHEMBL10862560 | 0.68 | NPSR1 (0.45) | KDM4EALDH1A1HPGDMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522277-A1 | Process for the preparation of 9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1993-01-13 | — | — | EP | disclosed |