Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606905 | 0.84 | MEN1 (0.47) | KDM4EMAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL8155555 | 0.80 | KDM4E (0.42) | KDM4EADRA2BMAPK1KMT2AMEN1 | |
| SCHEMBL8120918 | 0.78 | KDM4E (0.49) | KDM4EADRA2BMAPK1KMT2AMEN1 | |
| SCHEMBL8154760 | 0.74 | KDM4E (0.46) | KDM4EADRA2BMAPK1KMT2AMEN1 | |
| SCHEMBL9469723 | 0.74 | KDM4E (0.47) | KDM4EADRA2BMAPK1KMT2AMEN1 | |
| SCHEMBL9016703 | 0.73 | MAPT (0.41) | KDM4EMAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9565709 | 0.73 | KDM4E (0.44) | KDM4EADRA2BMAPK1KMT2AMEN1 | |
| SCHEMBL1187294 | 0.72 | PTPN1 (0.38) | MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30194898 | 0.72 | PTPN1 (0.38) | MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3611468 | 0.72 | KDM4E (0.42) | KDM4EADRA2BMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675880-B1 | QUINOLINE DISULFIDES AS INTERMEDIATES | ARCHIMICA SPA (IT) | 2000-01-05 | — | — | EP | claimed |
| US-5731433-A | Process for the preparation of rufloxacin and salts thereof | ARCHIMICA SPA (IT) | 1998-03-24 | — | — | US | disclosed |
| EP-0725785-B1 | PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS THEREOF | ARCHIMICA SPA (IT) | 1997-07-23 | — | — | EP | disclosed |