Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927584 | 1.00 | HSD17B2 (0.42) | HSD17B2GRIN2CMTNR1BL3MBTL1TACR1 | |
| SCHEMBL8923597 | 1.00 | HSD17B2 (0.42) | HSD17B2GRIN2CMTNR1BL3MBTL1TACR1 | |
| SCHEMBL8926073 | 0.90 | GRIN2C (0.40) | HSD17B2GRIN2CTACR1MEN1KMT2A | |
| SCHEMBL8925866 | 0.90 | GRIN2C (0.40) | HSD17B2GRIN2CTACR1MEN1KMT2A | |
| SCHEMBL9204527 | 0.86 | TACR1 (0.41) | HSD17B2MTNR1BTACR1 | |
| SCHEMBL8939874 | 0.86 | TACR1 (0.41) | HSD17B2MTNR1BTACR1 | |
| SCHEMBL8926027 | 0.81 | HSD17B2 (0.40) | HSD17B2TACR1OPRK1 | |
| SCHEMBL8925651 | 0.81 | HSD17B2 (0.40) | HSD17B2TACR1OPRK1 | |
| SCHEMBL8924315 | 0.81 | HSD17B2 (0.36) | HSD17B2TACR1 | |
| SCHEMBL8925754 | 0.81 | HSD17B2 (0.36) | HSD17B2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532456-A1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | claimed |