Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204527 | 1.00 | TACR1 (0.41) | TACR1TP53HSD17B2LMNAMTNR1B | |
| SCHEMBL8925754 | 0.90 | HSD17B2 (0.36) | TACR1TP53HSD17B2LMNAHPGD | |
| SCHEMBL8924315 | 0.90 | HSD17B2 (0.36) | TACR1TP53HSD17B2LMNAHPGD | |
| SCHEMBL8926073 | 0.88 | GRIN2C (0.40) | TACR1HSD17B2LMNAALDH1A1KDM4E | |
| SCHEMBL8925866 | 0.88 | GRIN2C (0.40) | TACR1HSD17B2LMNAALDH1A1KDM4E | |
| SCHEMBL8925804 | 0.87 | MTNR1B (0.38) | TACR1TP53MTNR1BHPGD | |
| SCHEMBL8925221 | 0.87 | MTNR1B (0.38) | TACR1TP53MTNR1BHPGD | |
| SCHEMBL8927584 | 0.86 | HSD17B2 (0.42) | TACR1HSD17B2MTNR1B | |
| SCHEMBL9565771 | 0.86 | HSD17B2 (0.42) | TACR1HSD17B2MTNR1B | |
| SCHEMBL8923597 | 0.86 | HSD17B2 (0.42) | TACR1HSD17B2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532456-B1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | claimed |
| EP-0532456-A1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | claimed |
| US-5585415-A | A FINE, UNIFORM SURFACE WRINKLING EFFECT; USING AN ACYLPHOSPHINE AND AN ACETOPHENONE DERIVATIVE AS PHOTOINITIATORS | PPG INDUSTRIES, INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0693002-A1 | COMPOSITIONS AND METHODS FOR PRODUCING HIGH GLOSS RADIATON CURABLE COATINGS | PPG INDUSTRIES INC (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0662991-A1 | PIGMENTED COMPOSITIONS AND METHODS FOR PRODUCING RADIATION CURABLE COATINGS OF VERY LOW GLOSS | PPG INDUSTRIES, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1995008596-A1 | FLAT, DARK PIGMENTED RADIATION CURABLE COATING COMPOSITIONS | PPG INDUSTRIES, INC. (US) | 1995-03-30 | — | — | WO | disclosed |
| EP-0532456-B1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994022596-A1 | COMPOSITIONS AND METHODS FOR PRODUCING HIGH GLOSS RADIATON CURABLE COATINGS | PPG INDUSTRIES, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994007958-A1 | PIGMENTED COMPOSITIONS AND METHODS FOR PRODUCING RADIATION CURABLE COATINGS OF VERY LOW GLOSS | PPG INDUSTRIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0532456-A1 | 1-Acylpiperidine derivatives and their use as substance P antagonists | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |