Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042856 | 0.81 | ALDH1A1 (0.59) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31005115 | 0.81 | AKR1C3 (0.50) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11761776 | 0.78 | AKR1C3 (0.56) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11123949 | 0.78 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6869657 | 0.76 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10955387 | 0.75 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4568726 | 0.75 | SRD5A2 (0.50) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11760101 | 0.74 | AKR1C3 (0.43) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8578095 | 0.74 | AKR1C3 (0.55) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL533764 | 0.74 | ALDH1A1 (0.50) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526951-A1 | 3-Phenyl benzo b thiophenes as pesticidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-10 | — | — | EP | disclosed |