Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | KIF11 | P52732 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014610 | 0.83 | HPGD (1.00) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL12054668 | 0.82 | KEAP1 (0.75) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL179127 | 0.81 | HPGD (0.73) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL518113 | 0.81 | HPGD (0.73) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL2365093 | 0.79 | PTPRB (0.50) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL19567610 | 0.79 | HPGD (0.70) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL1752625 | 0.79 | HPGD (0.70) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL21629439 | 0.79 | HPGD (0.70) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL1752626 | 0.79 | HPGD (0.70) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL4175815 | 0.79 | HPGD (0.70) | HPGDSMN1; SMN2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534246-A2 | Benzylamine derivatives and medicines with antiarrhythmic activity containing them | BASF Aktiengesellschaft (DE) | 1993-03-31 | — | — | EP | disclosed |