⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387695 | 0.69 | — | — | |
| SCHEMBL3744041 | 0.69 | — | — | |
| SCHEMBL11734409 | 0.69 | — | — | |
| SCHEMBL122102 | 0.69 | — | — | |
| SCHEMBL538437 | 0.69 | — | — | |
| SCHEMBL4108957 | 0.69 | — | — | |
| SCHEMBL908521 | 0.69 | — | — | |
| SCHEMBL8031726 | 0.65 | — | — | |
| SCHEMBL2299219 | 0.64 | PTPN1 (0.41) | — | |
| SCHEMBL2379059 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | CANNIZZARO CARINA | 2009-09-10 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7427636-B2 | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-09-23 | — | — | US | disclosed |
| EP-0571031-A2 | Process for the preparation of savoury flavours | QUEST INTERNATIONAL B.V. (NL) | 1993-11-24 | — | — | EP | disclosed |
| US-4148995-A | FROM AN AZETIDINONE AND A FURANONE, MULTISTEP | Petrzilka, Theodor (CH) | 1979-04-10 | — | — | US | disclosed |