Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565878 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL27853501 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL8546366 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL31575452 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL29979726 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL3507300 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL28280199 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL28280177 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL27383020 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL3110030 | 0.74 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | disclosed |