Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344670 | 0.80 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2GRM5 | |
| SCHEMBL2745018 | 0.79 | PPARG (0.41) | — | |
| SCHEMBL9566280 | 0.77 | TBXA2R (0.38) | — | |
| SCHEMBL2914346 | 0.77 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2GRM5 | |
| SCHEMBL4822404 | 0.76 | PDCD1 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL27138894 | 0.76 | KCNH2 (0.31) | — | |
| SCHEMBL31413495 | 0.76 | KCNH2 (0.31) | — | |
| SCHEMBL31124766 | 0.75 | TSHR (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL30563707 | 0.74 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9347235 | 0.74 | ESR1 (0.43) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |