Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566303 | 0.85 | NPSR1 (0.40) | TBXA2RNPSR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9566346 | 0.81 | SMYD2 (0.30) | — | |
| SCHEMBL9566270 | 0.78 | CYP4A11 (0.40) | NPSR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9566258 | 0.77 | SMYD2 (0.32) | — | |
| SCHEMBL9566211 | 0.75 | FFAR1 (0.40) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL8701680 | 0.74 | TBXA2R (0.44) | TBXA2RNPSR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9566301 | 0.73 | AKR1B1 (0.39) | — | |
| SCHEMBL30159307 | 0.72 | FFAR4 (0.47) | FFAR1FFAR4THRATHRB | |
| SCHEMBL305587 | 0.71 | CYP4F2 (0.56) | — | |
| SCHEMBL9566213 | 0.71 | TBXA2R (0.43) | TBXA2RNPSR1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |