Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GRM8 | O00222 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566460 | 1.00 | HRH3 (0.36) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL9566371 | 1.00 | HRH3 (0.36) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL9566481 | 1.00 | HRH3 (0.36) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL15415973 | 1.00 | HRH3 (0.36) | HRH3GRM4CYP1A2GRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL22636190 | 0.89 | SSTR4 (0.33) | HRH3 | |
| SCHEMBL29464322 | 0.88 | SLC6A1 (0.38) | HRH3CYP1A2GRM2GRM3TSHR | |
| SCHEMBL23797246 | 0.87 | HRH3 (0.45) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL22616173 | 0.87 | HRH3 (0.45) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL1709272 | 0.87 | HRH3 (0.45) | HRH3GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL18149905 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | claimed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |