Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SI | P14410 | 2/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978594 | 0.87 | TDP1 (0.59) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL16653966 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL22468103 | 0.78 | PTPN1 (0.42) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL10549402 | 0.77 | MGAM (0.54) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL9566423 | 0.77 | HTR2B (0.58) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL1287837 | 0.76 | ALDH1A1 (0.74) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL30535903 | 0.76 | ALDH1A1 (0.74) | ALDH1A1TDP1L3MBTL1MGAMGAA | |
| SCHEMBL17046876 | 0.76 | SMN1; SMN2 (0.71) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30468191 | 0.76 | SMN1; SMN2 (0.71) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3834788 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |