SCHEMBL9566604

SCHEMBL9566604

Nc1ccc(N2C(=O)c3cccc(N)c3C2=O)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.77
PABPC1 P11940 1/20 0.77
ADORA2A P29274 1/20 0.76
DPP4 P27487 1/20 0.58
ALDH1A1 P00352 3/20 0.47
KMT2A Q03164 3/20 0.47
USP2 O75604 2/20 0.47
KEAP1 Q14145 2/20 0.47
NFE2L2 Q16236 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPC1 O15118 1/20 0.47
TSHR P16473 1/20 0.47
CASP1 P29466 1/20 0.47
RAB9A P51151 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513204 0.87 HSPA1A (1.00) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL31259838 0.87 HSPA1A (1.00) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL31061260 0.86 ADORA2A (1.00) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9566623 0.86 HSPA1A (0.73) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9468703 0.85 HSPA1A (0.71) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9468821 0.85 HSPA1A (0.71) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9453245 0.85 HSPA1A (0.57) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9468815 0.84 HSPA1A (0.80) HSPA1APABPC1ADORA2ADPP4ALDH1A1
SCHEMBL9571719 0.83 HSPA1A (0.69) HSPA1APABPC1ADORA2ADPP4KDM4E
SCHEMBL9566668 0.83 HSPA1A (0.73) HSPA1APABPC1ADORA2ADPP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed