Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566876 | 0.88 | MEN1 (0.69) | MEN1KMT2AAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9566822 | 0.87 | MEN1 (0.74) | MEN1KMT2AAHRP4HTMMAPT | |
| SCHEMBL9566729 | 0.86 | KMT2A (0.66) | MEN1KMT2AAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9566794 | 0.84 | MEN1 (0.74) | MEN1KMT2AAHRALDH1A1P4HTM | |
| SCHEMBL9566763 | 0.83 | AHR (0.69) | MEN1KMT2AAHRSMN1; SMN2P4HTM | |
| SCHEMBL9566749 | 0.81 | KMT2A (0.66) | MEN1KMT2AAHRSMN1; SMN2P4HTM | |
| SCHEMBL9566759 | 0.80 | CXCR2 (0.55) | ALDH1A1P4HTMNPC1RAB9A | |
| SCHEMBL3795003 | 0.78 | MEN1 (0.80) | MEN1KMT2AAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9566745 | 0.78 | P4HTM (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6927927 | 0.77 | MEN1 (0.66) | MEN1KMT2AAHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |