Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.66 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566763 | 0.88 | AHR (0.69) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566822 | 0.87 | MEN1 (0.74) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566783 | 0.86 | RAB9A (0.63) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL6927927 | 0.86 | MEN1 (0.66) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566756 | 0.84 | RAB9A (0.57) | KMT2AMEN1P4HTMKDM4ENPC1 | |
| SCHEMBL9566794 | 0.84 | MEN1 (0.74) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566729 | 0.84 | KMT2A (0.66) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566876 | 0.83 | MEN1 (0.69) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566733 | 0.81 | MEN1 (0.66) | KMT2AMEN1AHRP4HTMMAPT | |
| SCHEMBL9566738 | 0.81 | CXCR2 (0.64) | KMT2AMEN1P4HTMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |