Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.64 |
| ▸ | SLC37A4 | O43826 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.55 |
| ▸ | PSMG3 | Q9BT73 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566910 | 0.86 | IDO1 (0.58) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL29454426 | 0.79 | IDO1 (0.83) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL29711773 | 0.78 | SLC37A4 (1.00) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL20313458 | 0.76 | IDO1 (0.74) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL18621792 | 0.75 | CYP3A4 (0.87) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL31644226 | 0.75 | IDO1 (0.65) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| Diffractaic Acid SCHEMBL3459615 | 0.74 | CYP3A4 (1.00) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL18622144 | 0.74 | CYP3A4 (0.84) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL29662753 | 0.74 | CYP3A4 (0.84) | IDO1SLC37A4CYP3A4KMT2AMEN1 | |
| SCHEMBL29662752 | 0.74 | CYP3A4 (0.84) | IDO1SLC37A4CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547231-A1 | PHOSPHOLIPASE A2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |