SCHEMBL9566973

SCHEMBL9566973

C=C(C)C(=O)OCCOC(=O)N(O)CC

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
TSHR P16473 4/20 0.50
ALDH1A1 P00352 3/20 0.37
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14999216 0.83 THRB (0.58) THRBTSHRALDH1A1POLBAPEX1
Propane SCHEMBL11405097 0.80 THRB (0.75) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.79 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.79 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4908328 0.79 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2921354 0.78 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Trimethylammonium SCHEMBL28556159 0.78 THRB (0.65) THRBTSHRALDH1A1POLBAPEX1
Butane SCHEMBL1244632 0.78 THRB (0.72) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10082702 0.77 THRB (0.51) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL955493 0.77 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0555628-A2 Process for preparing isocyanates NIPPON SHOKUBAI CO., LTD. (JP) 1993-08-18 EP disclosed