Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567207 | 1.00 | CHRM1 (0.36) | CHRM1FAAHAGTR2MGLLCYP19A1 | |
| SCHEMBL9567109 | 1.00 | CHRM1 (0.36) | CHRM1FAAHAGTR2MGLLCYP19A1 | |
| SCHEMBL9595532 | 1.00 | CHRM1 (0.36) | CHRM1FAAHAGTR2MGLLCYP19A1 | |
| SCHEMBL9595541 | 1.00 | CHRM1 (0.36) | CHRM1FAAHAGTR2MGLLCYP19A1 | |
| SCHEMBL9567095 | 0.88 | FAAH (0.41) | CHRM1FAAHMGLLCYP19A1LMNA | |
| SCHEMBL9567094 | 0.88 | FAAH (0.41) | CHRM1FAAHMGLLCYP19A1LMNA | |
| SCHEMBL9567112 | 0.88 | FAAH (0.41) | CHRM1FAAHMGLLCYP19A1LMNA | |
| SCHEMBL9198124 | 0.87 | CHRM1 (0.40) | CHRM1FAAHAGTR2MGLLCYP19A1 | |
| SCHEMBL9567224 | 0.87 | NPSR1 (0.44) | CHRM1FAAHMGLLSIGMAR1ELANE | |
| SCHEMBL9567228 | 0.87 | NPSR1 (0.44) | CHRM1FAAHMGLLSIGMAR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001192-A1 | 2-(2-SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-01-21 | — | — | WO | disclosed |
| EP-0522504-A1 | 2-(2-substituted pyrrolidinylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |