Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595744 | 1.00 | NR1H2 (0.36) | NR1H2TSHRUCHL1ALDH1A1CYP1A2 | |
| SCHEMBL4300613 | 0.84 | UCHL1 (0.37) | NR1H2TSHRUCHL1ALDH1A1CYP1A2 | |
| SCHEMBL18577100 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL3832206 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL3832181 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL2809688 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL4300617 | 0.84 | UCHL1 (0.37) | NR1H2TSHRUCHL1ALDH1A1CYP1A2 | |
| SCHEMBL2708045 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL29203075 | 0.84 | UCHL1 (0.39) | NR1H2UCHL1CYP1A2POLBCYP3A4 | |
| SCHEMBL29548437 | 0.84 | UCHL1 (0.37) | NR1H2UCHL1ALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522504-A1 | 2-(2-substituted pyrrolidinylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |