SCHEMBL9567378

SCHEMBL9567378

CCCCOCC(O)COc1ccc(-c2nc(-c3ccc(C)cc3)nc(-c3ccc(C)cc3)n2)c(O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 1/20 0.39
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.36
ADRB2 P07550 2/20 0.36
ADRB1 P08588 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254047 0.97 PLA2G4B (0.44) PLA2G4BACACBACACAHTTUSP2
SCHEMBL13171929 0.92 PLA2G4B (0.41) PLA2G4BACACBACACAHTTUSP2
SCHEMBL15127483 0.92 CASR (0.42) PLA2G4BALDH1A1MAPTNPC1MEN1
SCHEMBL27974339 0.92 PLA2G4B (0.39) PLA2G4BACACBACACAALDH1A1MAPT
SCHEMBL29363492 0.91 PLA2G4B (0.45) PLA2G4BALDH1A1MAPTNPC1RAB9A
SCHEMBL38782 0.91 PLA2G4B (0.45) PLA2G4BALDH1A1MAPTNPC1RAB9A
SCHEMBL6334661 0.91 PLA2G4B (0.41) PLA2G4BALDH1A1MAPTMEN1KMT2A
SCHEMBL8517433 0.90 PLA2G4B (0.42) PLA2G4BALDH1A1MAPTNPC1RAB9A
SCHEMBL8383224 0.90 PLA2G4B (0.42) PLA2G4BALDH1A1MAPTNPC1RAB9A
SCHEMBL15721408 0.89 PLA2G4B (0.39) PLA2G4BACACBACACAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530135-A1 UV-absorber containing photographic material CIBA-GEIGY AG (CH) 1993-03-03 EP disclosed